Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors during the central nervous method, conolidine modulates alternate molecular targets. A Science Advancements review found that conolidine interacts While using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availab... https://conolidinepainrelief00752.liberty-blog.com/37914847/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview