Pentobarbital increases amounts of vortioxetine by raising metabolism. Modify Therapy/Keep an eye on Carefully. Consider escalating the vortioxetine dose when coadministered with strong CYP inducers for >14 times; not to exceed 3 instances first vortioxetine dose. pentobarbital will decrease the extent or impact of amiodarone by influencing hepatic/intestinal enzyme CYP3A4 https://henryd577jzo7.blog4youth.com/profile